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What Are Ibuprofen Liquid Capsules 400mg Used For?
When pain strikes — whether it's a throbbing headache, a stiff back, or the monthly misery of period pain — you want something that gets to work quickly. Ibuprofen liquid capsules 400mg, sold as Nurofen Express, are designed to do exactly that. Each soft liquid-filled capsule contains 400mg of ibuprofen, a well-established non-steroidal anti-inflammatory drug (NSAID) that tackles pain, fever, and inflammation at the source. The liquid formulation means the active ingredient is released rapidly once swallowed, making it a popular choice for people who need fast, reliable relief.
Nurofen Express 400mg Liquid Capsules are available over the counter without a prescription and are suitable for adults and young people aged 12 and over. You can find them alongside other trusted options in our pain relief collection, where we stock a range of analgesics to suit different needs and preferences.
How Do Nurofen Express Liquid Capsules Work?
Ibuprofen belongs to the NSAID class of medicines. It works by blocking the activity of cyclo-oxygenase (COX) enzymes — specifically COX-1 and COX-2 — which are responsible for producing prostaglandins. Prostaglandins are chemical messengers that sensitise nerve endings to pain, trigger inflammation, and raise body temperature. By reducing prostaglandin production, ibuprofen helps to:
- Relieve mild to moderate pain, including headaches, dental pain, and muscular aches
- Reduce inflammation in conditions such as sprains and strains
- Lower fever (pyrexia) in adults and children aged 12 and over
- Ease the discomfort of period pain (dysmenorrhoea)
The liquid-filled capsule format is key to Nurofen Express's speed of action. Unlike standard compressed tablets, which must first dissolve before the drug can be absorbed, the liquid inside the capsule is already in solution. This means absorption through the gastrointestinal tract begins sooner after swallowing.
Who Is Nurofen Express 400mg Suitable For?
These capsules are intended for adults and adolescents aged 12 years and over. They are particularly well suited to people who:
- Need fast-acting relief from headaches, migraines, or tension headaches
- Experience regular period pain or back pain
- Have a fever and want an alternative to paracetamol
- Prefer a capsule format over standard tablets
They are not suitable for children under 12, people with known hypersensitivity to ibuprofen or aspirin, those with active peptic ulcers, or anyone in the third trimester of pregnancy. If you have asthma, kidney disease, heart failure, or a history of gastrointestinal bleeding, speak to your pharmacist or GP before use.
How Do Nurofen Express Liquid Capsules Compare to Standard Ibuprofen Tablets?
| Feature | Nurofen Express 400mg Liquid Capsules | Standard Ibuprofen 400mg Tablets |
|---|---|---|
| Formulation | Liquid-filled soft capsule | Compressed solid tablet |
| Speed of absorption | Faster — liquid already in solution | Slower — tablet must dissolve first |
| Active ingredient | Ibuprofen 400mg | Ibuprofen 400mg |
| Suitable age | 12 years and over | 12 years and over (dose-dependent) |
How Should You Store Nurofen Express 400mg Liquid Capsules?
Store your ibuprofen liquid capsules 400mg below 25°C in a dry place, away from direct sunlight. Keep the pack out of sight and reach of children at all times. Do not use the capsules after the expiry date printed on the packaging. If you are unsure whether a medicine is still safe to use, your local pharmacist can advise you — and many pharmacies offer safe disposal services for unwanted medicines.
If you are managing multiple health conditions and need support beyond pain relief — for example, if you also experience digestive discomfort — you may find our indigestion collection helpful, as NSAIDs like ibuprofen can sometimes irritate the stomach lining.
This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.
Nurofen Express 400mg Liquid Capsules - 20 specifications
| Treatment category | Pain relief / Anti-inflammatory / Antipyretic |
| Active ingredient | Ibuprofen 400mg |
| Mechanism of action | COX-1 and COX-2 enzyme inhibitor; reduces prostaglandin synthesis |
| Drug class | Non-steroidal anti-inflammatory drug (NSAID) |
| Preparation | Liquid-filled soft capsule |
| Route of administration | Oral |
| Strengths | 400mg ibuprofen per capsule |
| Pack size | 20 capsules |
| UK classification | General Sale List (GSL) |
| Suitable for | Adults and young people aged 12 years and over |
| Effective for | Headache, period pain, dental pain, muscular pain, fever, cold and flu symptoms |
Specifications of Nurofen Express 400mg Liquid Capsules - 20
What Is Nurofen Express 400mg and What Is It Used For?
Nurofen Express 400mg Liquid Capsules contain ibuprofen, a well-known NSAID used to relieve mild to moderate pain and reduce fever. The liquid-filled capsule format is designed to allow faster absorption compared to conventional solid tablets. This product is licensed for use in adults and adolescents aged 12 and over for the short-term treatment of pain — including headaches, dental pain, period pain, back pain, and muscular aches — as well as for reducing fever associated with colds and flu.
What Do You Need to Know Before Using Nurofen Express 400mg?
Before taking these capsules, it is important to check whether they are appropriate for you. Do not take Nurofen Express if any of the following apply:
- You are allergic to ibuprofen, aspirin, or any other NSAID
- You have or have previously had a peptic ulcer or gastrointestinal bleeding
- You are in the third trimester of pregnancy (weeks 28 onwards)
- You have severe heart failure, severe kidney failure, or severe liver failure
- You are under 12 years of age
Speak to your pharmacist or GP before taking this medicine if you have asthma, Crohn's disease, ulcerative colitis, high blood pressure, or a history of heart disease. The following medicines may interact with ibuprofen:
- Aspirin or other NSAIDs (increased risk of side effects)
- Warfarin or other anticoagulants (increased bleeding risk)
- SSRIs such as fluoxetine (increased risk of gastrointestinal bleeding)
- Antihypertensives including ACE inhibitors and diuretics (reduced effectiveness)
- Lithium and methotrexate (ibuprofen may increase their plasma levels)
- Corticosteroids (increased risk of gastrointestinal ulceration)
How Should You Use Nurofen Express 400mg Liquid Capsules?
Always take this medicine exactly as described on the label or as directed by your pharmacist. The capsules should be swallowed whole with a full glass of water — do not chew, crush, or break them. Taking them with food or milk can help reduce the chance of stomach irritation.
- Check the expiry date on the pack before use
- Swallow one capsule whole with a full glass of water
- Take with or after food to protect your stomach
- Wait at least four to six hours before taking another dose
- Do not take more than three capsules in any 24-hour period
- Stop taking and seek medical advice if symptoms worsen or do not improve within three days (fever) or ten days (pain)
| Indication | Age Group | Dose | Frequency |
|---|---|---|---|
| Pain / Fever | Adults & young people 12+ | 1 capsule (400mg) | Up to 3 times daily; at least 4–6 hours apart |
| Pain / Fever | Under 12 years | Not suitable | Not applicable |
If you are also dealing with cold or flu symptoms alongside pain, you may find it useful to browse our cold and flu collection for complementary products to support your recovery.
What Are the Possible Side Effects of Nurofen Express 400mg?
Like all medicines, ibuprofen can cause side effects, although not everyone experiences them. The most common ones tend to affect the digestive system. If you notice anything unusual or concerning, stop taking the capsules and speak to a pharmacist or GP promptly.
Common side effects (may affect up to 1 in 10 people):
- Nausea or vomiting
- Indigestion or heartburn
- Stomach pain or discomfort
- Diarrhoea or constipation
Less common side effects (may affect up to 1 in 100 people):
- Headache or dizziness
- Skin rash or itching
- Fluid retention (oedema)
- Raised blood pressure
Serious but rare side effects include gastrointestinal bleeding, allergic reactions (including anaphylaxis), and worsening of asthma. Seek emergency medical help immediately if you experience difficulty breathing, swelling of the face or throat, or blood in your stools.
How Should You Store Nurofen Express 400mg Liquid Capsules?
Correct storage helps maintain the safety and effectiveness of your medicine. Follow these guidelines:
- Store below 25°C in a cool, dry place
- Keep away from direct sunlight and moisture
- Keep out of sight and reach of children
- Do not use after the expiry date printed on the carton
- Do not store in a bathroom or near a sink
- Return unused or expired medicines to a pharmacy for safe disposal — do not flush or bin them
If you are supporting someone with a long-term condition who takes multiple medicines, it may also be worth exploring our vitamins and supplements collection to support overall wellbeing alongside any pain management plan.
References
- https://www.nhs.uk/medicines/ibuprofen-for-adults/
- https://www.nhs.uk/medicines/ibuprofen-for-adults/side-effects-of-ibuprofen/
- https://www.nhs.uk/medicines/ibuprofen-for-adults/who-can-and-cannot-take-ibuprofen/
- https://www.nhs.uk/medicines/ibuprofen-for-adults/how-and-when-to-take-ibuprofen/
- https://www.nhs.uk/medicines/ibuprofen-for-adults/taking-ibuprofen-with-other-medicines-and-herbal-supplements/
- https://bnf.nice.org.uk/drugs/ibuprofen/
Written and reviewed by our qualified team
Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.
Frequently Asked Questions
Where can I buy Nurofen Express 400mg Liquid Capsules online in the UK?
You can buy Nurofen Express 400mg Liquid Capsules directly from Cured Pharmacy, a GPhC-registered online pharmacy in the UK. No prescription is needed as this is an over-the-counter medicine. Simply add to your basket and choose your preferred delivery option for convenient home delivery.
How do Nurofen Express 400mg Liquid Capsules work in the body?
Nurofen Express capsules contain ibuprofen, which works by inhibiting COX-1 and COX-2 enzymes in the body. This reduces the production of prostaglandins — the chemicals responsible for triggering pain, inflammation, and fever. The liquid-filled capsule format allows the ibuprofen to be absorbed into the bloodstream more quickly than a standard compressed tablet, which must first dissolve before absorption can begin.
How do I take Nurofen Express 400mg Liquid Capsules step by step?
Swallow one capsule whole with a full glass of water — never chew or break the capsule. Take it with or after food to help protect your stomach lining. Wait at least four to six hours before taking another dose, and do not exceed three capsules in any 24-hour period.
What is the correct dose of Nurofen Express 400mg for adults?
The recommended dose for adults and young people aged 12 and over is one 400mg capsule, taken up to three times daily. Always leave at least four to six hours between doses. Do not take more than three capsules in 24 hours unless directed by a doctor.
When is the best time to take Nurofen Express 400mg?
There is no single "best" time of day — take Nurofen Express when you need pain relief or when your fever is causing discomfort. However, always take it with or after food, regardless of the time of day, to reduce the risk of stomach irritation. If you are taking it for period pain, starting at the first sign of discomfort may help manage symptoms more effectively.
What are the side effects of Nurofen Express 400mg Liquid Capsules?
Common side effects include nausea, indigestion, stomach pain, and diarrhoea. Less commonly, some people experience headache, dizziness, or skin rash. Serious but rare reactions include gastrointestinal bleeding, severe allergic reactions, and worsening asthma — stop taking the capsules and seek urgent medical help if any of these occur.
How do I manage side effects of Nurofen Express 400mg?
Taking the capsule with food or a glass of milk is the most effective way to reduce stomach-related side effects such as nausea or indigestion. If stomach discomfort persists, speak to your pharmacist — they may suggest a suitable stomach-protecting medicine. Never take more than the recommended dose in an attempt to speed up relief, as this increases the risk of side effects.
Who should not take Nurofen Express 400mg Liquid Capsules?
This product is not suitable for children under 12, people allergic to ibuprofen or aspirin, those with active peptic ulcers, or anyone in the third trimester of pregnancy. People with severe heart, kidney, or liver failure should also avoid it. If you have asthma, inflammatory bowel disease, or high blood pressure, consult your GP or pharmacist before use.
Can I take Nurofen Express 400mg with other medicines?
Ibuprofen can interact with a number of medicines, including aspirin, warfarin, SSRIs, antihypertensives, lithium, methotrexate, and corticosteroids. These interactions can increase the risk of side effects or reduce the effectiveness of either medicine. Always tell your pharmacist about all medicines you are currently taking before starting Nurofen Express. You can browse our full pain relief range for alternative options if ibuprofen is not suitable for you.
Is Nurofen Express 400mg safe to take during pregnancy?
Nurofen Express must not be taken during the third trimester of pregnancy (from 28 weeks onwards) as it can harm the unborn baby and cause complications during labour. Use during the first and second trimesters should only be considered on the advice of a doctor or pharmacist, as ibuprofen is generally not recommended in pregnancy. Paracetamol is usually the preferred pain reliever during pregnancy — speak to your midwife or GP for personalised advice.
What happens if I miss a dose of Nurofen Express 400mg?
Nurofen Express is taken as needed for pain or fever rather than on a fixed schedule, so a "missed dose" is less relevant than with regular prescription medicines. If you need pain relief and it has been at least four to six hours since your last capsule, you can take another dose. Never double up to compensate for a missed dose.
How long can you take Nurofen Express 400mg for?
Nurofen Express is intended for short-term use only. For fever, do not use for more than three days without consulting a doctor. For pain, do not use for more than ten days without medical advice. If your symptoms persist or worsen, speak to your GP as there may be an underlying cause that needs investigation.
What are the alternatives to Nurofen Express 400mg Liquid Capsules?
If ibuprofen is not suitable for you, paracetamol is a commonly used alternative for mild to moderate pain and fever. Aspirin (for adults only) is another option, though it also carries gastrointestinal risks. For a broader selection of pain relief options, visit our pain relief collection to compare products and find the right fit for your needs.
Can I take Nurofen Express 400mg for a toothache?
Yes — ibuprofen is commonly used for dental pain and is often recommended by dentists for toothache relief. It helps reduce both the pain and any associated inflammation around the affected tooth. However, dental pain relief is a temporary measure; you should still see a dentist to address the underlying cause. If you need additional dental care products, our dental products collection may be helpful.
What are the latest studies on ibuprofen liquid capsules?
Research consistently supports ibuprofen as an effective analgesic and anti-inflammatory agent for mild to moderate pain. Studies comparing liquid-filled ibuprofen capsules to standard tablets have shown that the liquid formulation achieves higher peak plasma concentrations more quickly, which aligns with the faster onset of action reported by users. Ibuprofen remains one of the most widely studied over-the-counter medicines globally, with an established safety profile when used as directed for short-term pain relief.
Description
What Are Ibuprofen Liquid Capsules 400mg Used For?
When pain strikes — whether it's a throbbing headache, a stiff back, or the monthly misery of period pain — you want something that gets to work quickly. Ibuprofen liquid capsules 400mg, sold as Nurofen Express, are designed to do exactly that. Each soft liquid-filled capsule contains 400mg of ibuprofen, a well-established non-steroidal anti-inflammatory drug (NSAID) that tackles pain, fever, and inflammation at the source. The liquid formulation means the active ingredient is released rapidly once swallowed, making it a popular choice for people who need fast, reliable relief.
Nurofen Express 400mg Liquid Capsules are available over the counter without a prescription and are suitable for adults and young people aged 12 and over. You can find them alongside other trusted options in our pain relief collection, where we stock a range of analgesics to suit different needs and preferences.
How Do Nurofen Express Liquid Capsules Work?
Ibuprofen belongs to the NSAID class of medicines. It works by blocking the activity of cyclo-oxygenase (COX) enzymes — specifically COX-1 and COX-2 — which are responsible for producing prostaglandins. Prostaglandins are chemical messengers that sensitise nerve endings to pain, trigger inflammation, and raise body temperature. By reducing prostaglandin production, ibuprofen helps to:
- Relieve mild to moderate pain, including headaches, dental pain, and muscular aches
- Reduce inflammation in conditions such as sprains and strains
- Lower fever (pyrexia) in adults and children aged 12 and over
- Ease the discomfort of period pain (dysmenorrhoea)
The liquid-filled capsule format is key to Nurofen Express's speed of action. Unlike standard compressed tablets, which must first dissolve before the drug can be absorbed, the liquid inside the capsule is already in solution. This means absorption through the gastrointestinal tract begins sooner after swallowing.
Who Is Nurofen Express 400mg Suitable For?
These capsules are intended for adults and adolescents aged 12 years and over. They are particularly well suited to people who:
- Need fast-acting relief from headaches, migraines, or tension headaches
- Experience regular period pain or back pain
- Have a fever and want an alternative to paracetamol
- Prefer a capsule format over standard tablets
They are not suitable for children under 12, people with known hypersensitivity to ibuprofen or aspirin, those with active peptic ulcers, or anyone in the third trimester of pregnancy. If you have asthma, kidney disease, heart failure, or a history of gastrointestinal bleeding, speak to your pharmacist or GP before use.
How Do Nurofen Express Liquid Capsules Compare to Standard Ibuprofen Tablets?
| Feature | Nurofen Express 400mg Liquid Capsules | Standard Ibuprofen 400mg Tablets |
|---|---|---|
| Formulation | Liquid-filled soft capsule | Compressed solid tablet |
| Speed of absorption | Faster — liquid already in solution | Slower — tablet must dissolve first |
| Active ingredient | Ibuprofen 400mg | Ibuprofen 400mg |
| Suitable age | 12 years and over | 12 years and over (dose-dependent) |
How Should You Store Nurofen Express 400mg Liquid Capsules?
Store your ibuprofen liquid capsules 400mg below 25°C in a dry place, away from direct sunlight. Keep the pack out of sight and reach of children at all times. Do not use the capsules after the expiry date printed on the packaging. If you are unsure whether a medicine is still safe to use, your local pharmacist can advise you — and many pharmacies offer safe disposal services for unwanted medicines.
If you are managing multiple health conditions and need support beyond pain relief — for example, if you also experience digestive discomfort — you may find our indigestion collection helpful, as NSAIDs like ibuprofen can sometimes irritate the stomach lining.
This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.
Nurofen Express 400mg Liquid Capsules - 20 specifications
| Treatment category | Pain relief / Anti-inflammatory / Antipyretic |
| Active ingredient | Ibuprofen 400mg |
| Mechanism of action | COX-1 and COX-2 enzyme inhibitor; reduces prostaglandin synthesis |
| Drug class | Non-steroidal anti-inflammatory drug (NSAID) |
| Preparation | Liquid-filled soft capsule |
| Route of administration | Oral |
| Strengths | 400mg ibuprofen per capsule |
| Pack size | 20 capsules |
| UK classification | General Sale List (GSL) |
| Suitable for | Adults and young people aged 12 years and over |
| Effective for | Headache, period pain, dental pain, muscular pain, fever, cold and flu symptoms |
Specifications of Nurofen Express 400mg Liquid Capsules - 20
What Is Nurofen Express 400mg and What Is It Used For?
Nurofen Express 400mg Liquid Capsules contain ibuprofen, a well-known NSAID used to relieve mild to moderate pain and reduce fever. The liquid-filled capsule format is designed to allow faster absorption compared to conventional solid tablets. This product is licensed for use in adults and adolescents aged 12 and over for the short-term treatment of pain — including headaches, dental pain, period pain, back pain, and muscular aches — as well as for reducing fever associated with colds and flu.
What Do You Need to Know Before Using Nurofen Express 400mg?
Before taking these capsules, it is important to check whether they are appropriate for you. Do not take Nurofen Express if any of the following apply:
- You are allergic to ibuprofen, aspirin, or any other NSAID
- You have or have previously had a peptic ulcer or gastrointestinal bleeding
- You are in the third trimester of pregnancy (weeks 28 onwards)
- You have severe heart failure, severe kidney failure, or severe liver failure
- You are under 12 years of age
Speak to your pharmacist or GP before taking this medicine if you have asthma, Crohn's disease, ulcerative colitis, high blood pressure, or a history of heart disease. The following medicines may interact with ibuprofen:
- Aspirin or other NSAIDs (increased risk of side effects)
- Warfarin or other anticoagulants (increased bleeding risk)
- SSRIs such as fluoxetine (increased risk of gastrointestinal bleeding)
- Antihypertensives including ACE inhibitors and diuretics (reduced effectiveness)
- Lithium and methotrexate (ibuprofen may increase their plasma levels)
- Corticosteroids (increased risk of gastrointestinal ulceration)
How Should You Use Nurofen Express 400mg Liquid Capsules?
Always take this medicine exactly as described on the label or as directed by your pharmacist. The capsules should be swallowed whole with a full glass of water — do not chew, crush, or break them. Taking them with food or milk can help reduce the chance of stomach irritation.
- Check the expiry date on the pack before use
- Swallow one capsule whole with a full glass of water
- Take with or after food to protect your stomach
- Wait at least four to six hours before taking another dose
- Do not take more than three capsules in any 24-hour period
- Stop taking and seek medical advice if symptoms worsen or do not improve within three days (fever) or ten days (pain)
| Indication | Age Group | Dose | Frequency |
|---|---|---|---|
| Pain / Fever | Adults & young people 12+ | 1 capsule (400mg) | Up to 3 times daily; at least 4–6 hours apart |
| Pain / Fever | Under 12 years | Not suitable | Not applicable |
If you are also dealing with cold or flu symptoms alongside pain, you may find it useful to browse our cold and flu collection for complementary products to support your recovery.
What Are the Possible Side Effects of Nurofen Express 400mg?
Like all medicines, ibuprofen can cause side effects, although not everyone experiences them. The most common ones tend to affect the digestive system. If you notice anything unusual or concerning, stop taking the capsules and speak to a pharmacist or GP promptly.
Common side effects (may affect up to 1 in 10 people):
- Nausea or vomiting
- Indigestion or heartburn
- Stomach pain or discomfort
- Diarrhoea or constipation
Less common side effects (may affect up to 1 in 100 people):
- Headache or dizziness
- Skin rash or itching
- Fluid retention (oedema)
- Raised blood pressure
Serious but rare side effects include gastrointestinal bleeding, allergic reactions (including anaphylaxis), and worsening of asthma. Seek emergency medical help immediately if you experience difficulty breathing, swelling of the face or throat, or blood in your stools.
How Should You Store Nurofen Express 400mg Liquid Capsules?
Correct storage helps maintain the safety and effectiveness of your medicine. Follow these guidelines:
- Store below 25°C in a cool, dry place
- Keep away from direct sunlight and moisture
- Keep out of sight and reach of children
- Do not use after the expiry date printed on the carton
- Do not store in a bathroom or near a sink
- Return unused or expired medicines to a pharmacy for safe disposal — do not flush or bin them
If you are supporting someone with a long-term condition who takes multiple medicines, it may also be worth exploring our vitamins and supplements collection to support overall wellbeing alongside any pain management plan.
References
- https://www.nhs.uk/medicines/ibuprofen-for-adults/
- https://www.nhs.uk/medicines/ibuprofen-for-adults/side-effects-of-ibuprofen/
- https://www.nhs.uk/medicines/ibuprofen-for-adults/who-can-and-cannot-take-ibuprofen/
- https://www.nhs.uk/medicines/ibuprofen-for-adults/how-and-when-to-take-ibuprofen/
- https://www.nhs.uk/medicines/ibuprofen-for-adults/taking-ibuprofen-with-other-medicines-and-herbal-supplements/
- https://bnf.nice.org.uk/drugs/ibuprofen/
Written and reviewed by our qualified team
Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.
Frequently Asked Questions
Where can I buy Nurofen Express 400mg Liquid Capsules online in the UK?
You can buy Nurofen Express 400mg Liquid Capsules directly from Cured Pharmacy, a GPhC-registered online pharmacy in the UK. No prescription is needed as this is an over-the-counter medicine. Simply add to your basket and choose your preferred delivery option for convenient home delivery.
How do Nurofen Express 400mg Liquid Capsules work in the body?
Nurofen Express capsules contain ibuprofen, which works by inhibiting COX-1 and COX-2 enzymes in the body. This reduces the production of prostaglandins — the chemicals responsible for triggering pain, inflammation, and fever. The liquid-filled capsule format allows the ibuprofen to be absorbed into the bloodstream more quickly than a standard compressed tablet, which must first dissolve before absorption can begin.
How do I take Nurofen Express 400mg Liquid Capsules step by step?
Swallow one capsule whole with a full glass of water — never chew or break the capsule. Take it with or after food to help protect your stomach lining. Wait at least four to six hours before taking another dose, and do not exceed three capsules in any 24-hour period.
What is the correct dose of Nurofen Express 400mg for adults?
The recommended dose for adults and young people aged 12 and over is one 400mg capsule, taken up to three times daily. Always leave at least four to six hours between doses. Do not take more than three capsules in 24 hours unless directed by a doctor.
When is the best time to take Nurofen Express 400mg?
There is no single "best" time of day — take Nurofen Express when you need pain relief or when your fever is causing discomfort. However, always take it with or after food, regardless of the time of day, to reduce the risk of stomach irritation. If you are taking it for period pain, starting at the first sign of discomfort may help manage symptoms more effectively.
What are the side effects of Nurofen Express 400mg Liquid Capsules?
Common side effects include nausea, indigestion, stomach pain, and diarrhoea. Less commonly, some people experience headache, dizziness, or skin rash. Serious but rare reactions include gastrointestinal bleeding, severe allergic reactions, and worsening asthma — stop taking the capsules and seek urgent medical help if any of these occur.
How do I manage side effects of Nurofen Express 400mg?
Taking the capsule with food or a glass of milk is the most effective way to reduce stomach-related side effects such as nausea or indigestion. If stomach discomfort persists, speak to your pharmacist — they may suggest a suitable stomach-protecting medicine. Never take more than the recommended dose in an attempt to speed up relief, as this increases the risk of side effects.
Who should not take Nurofen Express 400mg Liquid Capsules?
This product is not suitable for children under 12, people allergic to ibuprofen or aspirin, those with active peptic ulcers, or anyone in the third trimester of pregnancy. People with severe heart, kidney, or liver failure should also avoid it. If you have asthma, inflammatory bowel disease, or high blood pressure, consult your GP or pharmacist before use.
Can I take Nurofen Express 400mg with other medicines?
Ibuprofen can interact with a number of medicines, including aspirin, warfarin, SSRIs, antihypertensives, lithium, methotrexate, and corticosteroids. These interactions can increase the risk of side effects or reduce the effectiveness of either medicine. Always tell your pharmacist about all medicines you are currently taking before starting Nurofen Express. You can browse our full pain relief range for alternative options if ibuprofen is not suitable for you.
Is Nurofen Express 400mg safe to take during pregnancy?
Nurofen Express must not be taken during the third trimester of pregnancy (from 28 weeks onwards) as it can harm the unborn baby and cause complications during labour. Use during the first and second trimesters should only be considered on the advice of a doctor or pharmacist, as ibuprofen is generally not recommended in pregnancy. Paracetamol is usually the preferred pain reliever during pregnancy — speak to your midwife or GP for personalised advice.
What happens if I miss a dose of Nurofen Express 400mg?
Nurofen Express is taken as needed for pain or fever rather than on a fixed schedule, so a "missed dose" is less relevant than with regular prescription medicines. If you need pain relief and it has been at least four to six hours since your last capsule, you can take another dose. Never double up to compensate for a missed dose.
How long can you take Nurofen Express 400mg for?
Nurofen Express is intended for short-term use only. For fever, do not use for more than three days without consulting a doctor. For pain, do not use for more than ten days without medical advice. If your symptoms persist or worsen, speak to your GP as there may be an underlying cause that needs investigation.
What are the alternatives to Nurofen Express 400mg Liquid Capsules?
If ibuprofen is not suitable for you, paracetamol is a commonly used alternative for mild to moderate pain and fever. Aspirin (for adults only) is another option, though it also carries gastrointestinal risks. For a broader selection of pain relief options, visit our pain relief collection to compare products and find the right fit for your needs.
Can I take Nurofen Express 400mg for a toothache?
Yes — ibuprofen is commonly used for dental pain and is often recommended by dentists for toothache relief. It helps reduce both the pain and any associated inflammation around the affected tooth. However, dental pain relief is a temporary measure; you should still see a dentist to address the underlying cause. If you need additional dental care products, our dental products collection may be helpful.
What are the latest studies on ibuprofen liquid capsules?
Research consistently supports ibuprofen as an effective analgesic and anti-inflammatory agent for mild to moderate pain. Studies comparing liquid-filled ibuprofen capsules to standard tablets have shown that the liquid formulation achieves higher peak plasma concentrations more quickly, which aligns with the faster onset of action reported by users. Ibuprofen remains one of the most widely studied over-the-counter medicines globally, with an established safety profile when used as directed for short-term pain relief.
