The Story
What Is Zovirax Cold Sore Cream and How Does It Help?
Cold sores are uncomfortable, and they have a habit of appearing at the worst possible moments. Zovirax cold sore cream is one of the most widely recognised antiviral treatments available over the counter in the UK, containing aciclovir 5% w/w as its active ingredient. It is specifically formulated to treat cold sores caused by the herpes simplex virus (HSV-1) on the lips and surrounding facial skin. You can browse a wider range of topical treatments in our creams and ointments collection.
Cold sores affect a significant proportion of the UK population. The NHS notes that most people are infected with HSV-1 during childhood, and the virus remains dormant in nerve cells, reactivating periodically throughout life. Triggers include stress, illness, sun exposure, and hormonal changes. Zovirax cold sore cream is designed to be used at the earliest sign of an outbreak — that familiar tingling or itching sensation — to help reduce both the severity and duration of the sore.
How Does Zovirax Cold Sore Cream Work Against the Virus?
The active ingredient, aciclovir, is an antiviral agent that targets the herpes simplex virus directly. It does not cure the virus permanently, but it does interfere with viral replication at the site of infection. Here is how it works:
- Aciclovir is absorbed into cells infected by HSV-1.
- Inside infected cells, it is converted by a viral enzyme (thymidine kinase) into its active form, aciclovir triphosphate.
- This active form blocks the viral DNA polymerase enzyme, preventing the virus from copying its genetic material.
- Without replication, the virus cannot spread further, and the cold sore heals more quickly.
Because aciclovir is selectively activated by a viral enzyme, it primarily affects infected cells rather than healthy ones. This targeted mechanism is why it has such a well-established safety profile for topical use.
Who Is Zovirax Cold Sore Cream Suitable For?
This cream is suitable for most adults and children aged 12 and over who experience recurrent cold sores on the lips or face. It is an over-the-counter medicine, meaning you do not need a prescription to purchase it. That said, it is not appropriate for everyone.
- Adults and adolescents aged 12 years and over with recurrent cold sores
- People who recognise their cold sore triggers and want to treat outbreaks early
- Those who prefer a topical treatment rather than an oral antiviral
- Individuals with a confirmed history of herpes simplex labialis (cold sores on the lips)
It is not suitable for use inside the mouth, nose, or eyes, and should not be applied to genital herpes. If you are immunocompromised — for example, due to HIV or chemotherapy — you should speak to your GP before using this product.
How Does Zovirax Cold Sore Cream Compare to Other Cold Sore Treatments?
| Feature | Zovirax Cold Sore Cream 2g | Penciclovir Cream (e.g. Vectavir) |
|---|---|---|
| Active ingredient | Aciclovir 5% w/w | Penciclovir 1% w/w |
| Application frequency | 5 times daily (every 4 hours) | Every 2 hours while awake |
| Treatment duration | 5 days | 4 days |
| Available OTC in UK | Yes | Yes |
How Should You Store Zovirax Cold Sore Cream?
Store Zovirax cold sore cream below 25°C in a dry place, away from direct sunlight. Do not freeze the tube. Always keep it out of the reach and sight of children. Check the expiry date printed on the tube before use — do not use the cream after the stated date. If you are looking for additional skin care products to support your lip and facial skin health, our dedicated collection has a range of options.
This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.
Zovirax Cold Sore Treatment Cream Tube 2g specifications
| Treatment category | Antiviral / Cold sore treatment |
| Active ingredient | Aciclovir 5% w/w |
| Mechanism of action | Inhibits herpes simplex virus DNA polymerase, preventing viral replication |
| Effective against | Herpes simplex virus type 1 (HSV-1) — cold sores on lips and face |
| Suitable for | Adults and children aged 12 years and over |
| Pack size | 2g tube |
| Strength | 5% w/w aciclovir |
| UK classification | Pharmacy (P) medicine |
| Drug class | Antiviral (nucleoside analogue) |
| Preparation | Cream |
| Route of administration | Topical (external use only) |
Specifications of Zovirax Cold Sore Treatment Cream Tube 2g
What Is Zovirax Cold Sore Cream and What Is It Used For?
Zovirax cold sore cream is a topical antiviral medicine used to treat cold sores on the lips and face in adults and children aged 12 and over. It contains aciclovir 5% w/w, which works by stopping the herpes simplex virus from replicating at the site of infection. It is classified as a Pharmacy (P) medicine in the UK, meaning it is available without a prescription but should be purchased from a registered pharmacy. It does not cure the herpes simplex virus — the virus remains in the body — but it can significantly reduce the duration and discomfort of an active cold sore outbreak when used promptly.
What Do You Need to Know Before Using Zovirax Cold Sore Cream?
Before applying this cream, read the following carefully. There are situations where this product may not be appropriate for you.
Do not use Zovirax cold sore cream if you:
- Are allergic to aciclovir, valaciclovir, propylene glycol, or any other ingredient in the cream
- Have a severely weakened immune system (e.g. due to HIV, organ transplant, or chemotherapy) — consult your GP first
- Need to treat cold sores inside the mouth, nose, or on the genitals — this product is for external facial use only
- Are under 12 years of age
Warnings and precautions:
- Avoid contact with the eyes and mucous membranes
- Do not apply to broken or inflamed skin beyond the cold sore itself
- Wash hands thoroughly before and after each application to avoid spreading the virus
- If you are pregnant or breastfeeding, speak to your pharmacist or GP before use
- Cold sores are contagious — avoid kissing or sharing utensils during an active outbreak
Known drug interactions:
- No clinically significant interactions are known at topical doses of aciclovir
- If you are taking oral antiviral medicines, inform your pharmacist before using this cream
How Should You Use Zovirax Cold Sore Cream?
Apply the cream as soon as you notice the first signs of a cold sore — tingling, itching, or redness. The earlier you start, the more effective it is likely to be. Follow these steps carefully:
- Wash your hands thoroughly with soap and water before touching the affected area.
- Squeeze a small amount of cream (approximately 1cm) onto a clean fingertip or cotton bud.
- Apply gently to the cold sore and the surrounding skin — do not rub vigorously.
- Wash your hands again immediately after application.
- Apply five times a day, roughly every four hours (excluding night-time sleep).
- Continue for five days. If the cold sore has not healed, treatment may be extended to ten days.
| Indication | Age Group | Dose | Frequency |
|---|---|---|---|
| Cold sore on lips/face | Adults and children aged 12+ | Small amount (~1cm strip) | 5 times daily, every 4 hours, for 5 days (up to 10 days if needed) |
| Cold sore on lips/face | Under 12 years | Not recommended | Consult a GP |
What Are the Possible Side Effects of Zovirax Cold Sore Cream?
Like all medicines, Zovirax cold sore cream can cause side effects, although not everyone experiences them. Most side effects are mild and localised to the area of application. If you are also managing other skin concerns, you may find our oral health collection useful for complementary lip and mouth care products.
Common side effects (may affect up to 1 in 10 people):
- Mild burning or stinging sensation at the application site
- Temporary itching or tingling after applying the cream
- Skin dryness or flaking around the treated area
Less common side effects (may affect up to 1 in 100 people):
- Redness or mild inflammation of the skin
- Contact dermatitis (skin irritation or rash)
- Peeling or cracking of the skin at the application site
Serious allergic reactions (hypersensitivity) are rare but can occur. Stop using the cream and seek immediate medical attention if you experience swelling of the face, lips, or throat, difficulty breathing, or a widespread skin rash.
How Should You Store Zovirax Cold Sore Cream?
Correct storage helps maintain the effectiveness of the cream throughout its shelf life. Follow these guidelines:
- Store below 25°C in a cool, dry place
- Do not freeze the tube
- Keep the tube tightly closed when not in use
- Keep out of the reach and sight of children
- Do not use after the expiry date printed on the tube and carton
- Do not dispose of medicines via wastewater or household waste — return unused medicines to your pharmacy
If you are looking for additional support during cold and flu season when cold sore outbreaks are more common, our cold and flu collection includes a range of relevant products to help you manage symptoms.
References
- https://www.nhs.uk/conditions/cold-sores/
- https://www.nhs.uk/medicines/aciclovir/
- https://www.nhs.uk/conditions/cold-sores/treatment/
- https://www.nhs.uk/conditions/herpes-simplex-eye-infections/
- https://bnf.nice.org.uk/drugs/aciclovir/
Written and reviewed by our qualified team
Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.
Frequently Asked Questions
Where can I buy Zovirax cold sore cream online in the UK?
You can buy Zovirax cold sore cream online in the UK directly from Cured Pharmacy for just £5.99. It is a Pharmacy (P) medicine available without a prescription. Simply add it to your basket and it will be dispatched quickly and discreetly to your door.
How does Zovirax cold sore cream work in the body?
Zovirax cold sore cream contains aciclovir 5%, which is absorbed into cells infected by the herpes simplex virus. Inside those cells, it is converted into an active form that blocks the viral enzyme responsible for copying the virus's DNA. This stops the virus from replicating and spreading, helping the cold sore heal faster.
How do I use Zovirax cold sore cream step by step?
Wash your hands, then apply a small amount of cream to the cold sore and surrounding skin five times a day, approximately every four hours. Continue for five days, or up to ten days if the sore has not fully healed. Always wash your hands again after applying to avoid spreading the virus to other areas.
When is the best time to start using Zovirax cold sore cream?
The best time to start using Zovirax cold sore cream is at the very first sign of an outbreak — typically a tingling, itching, or burning sensation on the lip before any blister appears. Starting treatment at this prodromal stage gives aciclovir the best opportunity to limit the severity of the cold sore. Waiting until a blister has fully formed reduces how effective the cream can be.
What are the side effects of Zovirax cold sore cream?
Most people tolerate Zovirax cold sore cream well. The most common side effects are mild and include a temporary burning or stinging sensation, itching, and skin dryness at the application site. Rarely, some people may experience a skin rash or contact dermatitis — if this happens, stop using the cream and speak to your pharmacist.
How do I manage side effects of Zovirax cold sore cream?
If you experience mild stinging or dryness, this usually settles on its own within a few minutes of application. Avoid rubbing the cream in vigorously — a gentle dabbing motion is sufficient. If irritation persists or worsens, discontinue use and consult your pharmacist or GP for further advice.
Who is eligible to use Zovirax cold sore cream?
Zovirax cold sore cream is suitable for adults and children aged 12 years and over who have cold sores on the lips or face caused by the herpes simplex virus. It is not recommended for children under 12, people with severely compromised immune systems without GP guidance, or for treating cold sores inside the mouth or on the genitals. If you are pregnant or breastfeeding, speak to your pharmacist before use.
What happens if I miss a dose of Zovirax cold sore cream?
If you forget to apply the cream at one of your scheduled times, apply it as soon as you remember and then continue with your regular schedule. Do not apply a double amount to make up for a missed application. Consistency is important — try to apply the cream at regular four-hourly intervals throughout the day for the best results.
What are the alternatives to Zovirax cold sore cream?
Alternatives to Zovirax cold sore cream include generic aciclovir 5% cream, which contains the same active ingredient at a lower price point, and penciclovir 1% cream (Vectavir), which is applied more frequently but over a shorter four-day course. For recurrent or severe outbreaks, your GP may consider prescribing oral aciclovir or valaciclovir tablets. You can explore related topical treatments in our creams and ointments collection.
How long does Zovirax cold sore cream take to work?
Zovirax cold sore cream is used for five days, and many people notice that the cold sore heals more quickly than it would without treatment, particularly when started early. Clinical studies have shown that aciclovir cream can reduce the duration of a cold sore episode when applied at the first sign of symptoms. If there is no improvement after ten days of use, consult your GP.
Can I use Zovirax cold sore cream during pregnancy?
If you are pregnant or breastfeeding, you should speak to your doctor or pharmacist before using Zovirax cold sore cream. Although topical aciclovir is only minimally absorbed through the skin and systemic exposure is very low, it is always sensible to seek professional advice before using any medicine during pregnancy. Your pharmacist can help you weigh up the benefits and any potential risks.
Can children use Zovirax cold sore cream?
Zovirax cold sore cream is not recommended for children under 12 years of age. For children aged 12 and over, it can be used in the same way as adults — five times daily for five days. If a younger child develops a cold sore, speak to your GP or pharmacist for appropriate advice and treatment options.
How long can you use Zovirax cold sore cream for?
The standard course of Zovirax cold sore cream is five days, which can be extended to ten days if the cold sore has not fully healed. It is not intended for long-term continuous use. If you are experiencing very frequent cold sore outbreaks — more than six per year — speak to your GP, who may consider oral antiviral therapy or other management strategies.
Does Zovirax cold sore cream interact with other medicines?
No clinically significant drug interactions are known at the topical doses of aciclovir used in Zovirax cold sore cream, as systemic absorption through the skin is very low. However, if you are already taking oral antiviral medicines such as aciclovir or valaciclovir tablets, let your pharmacist know before using this cream. Always inform your pharmacist of all medicines you are currently taking.
What are the latest studies on aciclovir cold sore cream?
Aciclovir 5% cream has been used clinically for decades and its efficacy in treating herpes simplex labialis is well established in published literature. Research consistently supports early application as the key factor in reducing outbreak duration and severity. For the most up-to-date clinical guidance, the NHS and BNF remain the primary reference sources for UK healthcare professionals and patients. You can also find related pain relief products if you need additional comfort during a cold sore outbreak.
Description
What Is Zovirax Cold Sore Cream and How Does It Help?
Cold sores are uncomfortable, and they have a habit of appearing at the worst possible moments. Zovirax cold sore cream is one of the most widely recognised antiviral treatments available over the counter in the UK, containing aciclovir 5% w/w as its active ingredient. It is specifically formulated to treat cold sores caused by the herpes simplex virus (HSV-1) on the lips and surrounding facial skin. You can browse a wider range of topical treatments in our creams and ointments collection.
Cold sores affect a significant proportion of the UK population. The NHS notes that most people are infected with HSV-1 during childhood, and the virus remains dormant in nerve cells, reactivating periodically throughout life. Triggers include stress, illness, sun exposure, and hormonal changes. Zovirax cold sore cream is designed to be used at the earliest sign of an outbreak — that familiar tingling or itching sensation — to help reduce both the severity and duration of the sore.
How Does Zovirax Cold Sore Cream Work Against the Virus?
The active ingredient, aciclovir, is an antiviral agent that targets the herpes simplex virus directly. It does not cure the virus permanently, but it does interfere with viral replication at the site of infection. Here is how it works:
- Aciclovir is absorbed into cells infected by HSV-1.
- Inside infected cells, it is converted by a viral enzyme (thymidine kinase) into its active form, aciclovir triphosphate.
- This active form blocks the viral DNA polymerase enzyme, preventing the virus from copying its genetic material.
- Without replication, the virus cannot spread further, and the cold sore heals more quickly.
Because aciclovir is selectively activated by a viral enzyme, it primarily affects infected cells rather than healthy ones. This targeted mechanism is why it has such a well-established safety profile for topical use.
Who Is Zovirax Cold Sore Cream Suitable For?
This cream is suitable for most adults and children aged 12 and over who experience recurrent cold sores on the lips or face. It is an over-the-counter medicine, meaning you do not need a prescription to purchase it. That said, it is not appropriate for everyone.
- Adults and adolescents aged 12 years and over with recurrent cold sores
- People who recognise their cold sore triggers and want to treat outbreaks early
- Those who prefer a topical treatment rather than an oral antiviral
- Individuals with a confirmed history of herpes simplex labialis (cold sores on the lips)
It is not suitable for use inside the mouth, nose, or eyes, and should not be applied to genital herpes. If you are immunocompromised — for example, due to HIV or chemotherapy — you should speak to your GP before using this product.
How Does Zovirax Cold Sore Cream Compare to Other Cold Sore Treatments?
| Feature | Zovirax Cold Sore Cream 2g | Penciclovir Cream (e.g. Vectavir) |
|---|---|---|
| Active ingredient | Aciclovir 5% w/w | Penciclovir 1% w/w |
| Application frequency | 5 times daily (every 4 hours) | Every 2 hours while awake |
| Treatment duration | 5 days | 4 days |
| Available OTC in UK | Yes | Yes |
How Should You Store Zovirax Cold Sore Cream?
Store Zovirax cold sore cream below 25°C in a dry place, away from direct sunlight. Do not freeze the tube. Always keep it out of the reach and sight of children. Check the expiry date printed on the tube before use — do not use the cream after the stated date. If you are looking for additional skin care products to support your lip and facial skin health, our dedicated collection has a range of options.
This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.
Zovirax Cold Sore Treatment Cream Tube 2g specifications
| Treatment category | Antiviral / Cold sore treatment |
| Active ingredient | Aciclovir 5% w/w |
| Mechanism of action | Inhibits herpes simplex virus DNA polymerase, preventing viral replication |
| Effective against | Herpes simplex virus type 1 (HSV-1) — cold sores on lips and face |
| Suitable for | Adults and children aged 12 years and over |
| Pack size | 2g tube |
| Strength | 5% w/w aciclovir |
| UK classification | Pharmacy (P) medicine |
| Drug class | Antiviral (nucleoside analogue) |
| Preparation | Cream |
| Route of administration | Topical (external use only) |
Specifications of Zovirax Cold Sore Treatment Cream Tube 2g
What Is Zovirax Cold Sore Cream and What Is It Used For?
Zovirax cold sore cream is a topical antiviral medicine used to treat cold sores on the lips and face in adults and children aged 12 and over. It contains aciclovir 5% w/w, which works by stopping the herpes simplex virus from replicating at the site of infection. It is classified as a Pharmacy (P) medicine in the UK, meaning it is available without a prescription but should be purchased from a registered pharmacy. It does not cure the herpes simplex virus — the virus remains in the body — but it can significantly reduce the duration and discomfort of an active cold sore outbreak when used promptly.
What Do You Need to Know Before Using Zovirax Cold Sore Cream?
Before applying this cream, read the following carefully. There are situations where this product may not be appropriate for you.
Do not use Zovirax cold sore cream if you:
- Are allergic to aciclovir, valaciclovir, propylene glycol, or any other ingredient in the cream
- Have a severely weakened immune system (e.g. due to HIV, organ transplant, or chemotherapy) — consult your GP first
- Need to treat cold sores inside the mouth, nose, or on the genitals — this product is for external facial use only
- Are under 12 years of age
Warnings and precautions:
- Avoid contact with the eyes and mucous membranes
- Do not apply to broken or inflamed skin beyond the cold sore itself
- Wash hands thoroughly before and after each application to avoid spreading the virus
- If you are pregnant or breastfeeding, speak to your pharmacist or GP before use
- Cold sores are contagious — avoid kissing or sharing utensils during an active outbreak
Known drug interactions:
- No clinically significant interactions are known at topical doses of aciclovir
- If you are taking oral antiviral medicines, inform your pharmacist before using this cream
How Should You Use Zovirax Cold Sore Cream?
Apply the cream as soon as you notice the first signs of a cold sore — tingling, itching, or redness. The earlier you start, the more effective it is likely to be. Follow these steps carefully:
- Wash your hands thoroughly with soap and water before touching the affected area.
- Squeeze a small amount of cream (approximately 1cm) onto a clean fingertip or cotton bud.
- Apply gently to the cold sore and the surrounding skin — do not rub vigorously.
- Wash your hands again immediately after application.
- Apply five times a day, roughly every four hours (excluding night-time sleep).
- Continue for five days. If the cold sore has not healed, treatment may be extended to ten days.
| Indication | Age Group | Dose | Frequency |
|---|---|---|---|
| Cold sore on lips/face | Adults and children aged 12+ | Small amount (~1cm strip) | 5 times daily, every 4 hours, for 5 days (up to 10 days if needed) |
| Cold sore on lips/face | Under 12 years | Not recommended | Consult a GP |
What Are the Possible Side Effects of Zovirax Cold Sore Cream?
Like all medicines, Zovirax cold sore cream can cause side effects, although not everyone experiences them. Most side effects are mild and localised to the area of application. If you are also managing other skin concerns, you may find our oral health collection useful for complementary lip and mouth care products.
Common side effects (may affect up to 1 in 10 people):
- Mild burning or stinging sensation at the application site
- Temporary itching or tingling after applying the cream
- Skin dryness or flaking around the treated area
Less common side effects (may affect up to 1 in 100 people):
- Redness or mild inflammation of the skin
- Contact dermatitis (skin irritation or rash)
- Peeling or cracking of the skin at the application site
Serious allergic reactions (hypersensitivity) are rare but can occur. Stop using the cream and seek immediate medical attention if you experience swelling of the face, lips, or throat, difficulty breathing, or a widespread skin rash.
How Should You Store Zovirax Cold Sore Cream?
Correct storage helps maintain the effectiveness of the cream throughout its shelf life. Follow these guidelines:
- Store below 25°C in a cool, dry place
- Do not freeze the tube
- Keep the tube tightly closed when not in use
- Keep out of the reach and sight of children
- Do not use after the expiry date printed on the tube and carton
- Do not dispose of medicines via wastewater or household waste — return unused medicines to your pharmacy
If you are looking for additional support during cold and flu season when cold sore outbreaks are more common, our cold and flu collection includes a range of relevant products to help you manage symptoms.
References
- https://www.nhs.uk/conditions/cold-sores/
- https://www.nhs.uk/medicines/aciclovir/
- https://www.nhs.uk/conditions/cold-sores/treatment/
- https://www.nhs.uk/conditions/herpes-simplex-eye-infections/
- https://bnf.nice.org.uk/drugs/aciclovir/
Written and reviewed by our qualified team
Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.
Frequently Asked Questions
Where can I buy Zovirax cold sore cream online in the UK?
You can buy Zovirax cold sore cream online in the UK directly from Cured Pharmacy for just £5.99. It is a Pharmacy (P) medicine available without a prescription. Simply add it to your basket and it will be dispatched quickly and discreetly to your door.
How does Zovirax cold sore cream work in the body?
Zovirax cold sore cream contains aciclovir 5%, which is absorbed into cells infected by the herpes simplex virus. Inside those cells, it is converted into an active form that blocks the viral enzyme responsible for copying the virus's DNA. This stops the virus from replicating and spreading, helping the cold sore heal faster.
How do I use Zovirax cold sore cream step by step?
Wash your hands, then apply a small amount of cream to the cold sore and surrounding skin five times a day, approximately every four hours. Continue for five days, or up to ten days if the sore has not fully healed. Always wash your hands again after applying to avoid spreading the virus to other areas.
When is the best time to start using Zovirax cold sore cream?
The best time to start using Zovirax cold sore cream is at the very first sign of an outbreak — typically a tingling, itching, or burning sensation on the lip before any blister appears. Starting treatment at this prodromal stage gives aciclovir the best opportunity to limit the severity of the cold sore. Waiting until a blister has fully formed reduces how effective the cream can be.
What are the side effects of Zovirax cold sore cream?
Most people tolerate Zovirax cold sore cream well. The most common side effects are mild and include a temporary burning or stinging sensation, itching, and skin dryness at the application site. Rarely, some people may experience a skin rash or contact dermatitis — if this happens, stop using the cream and speak to your pharmacist.
How do I manage side effects of Zovirax cold sore cream?
If you experience mild stinging or dryness, this usually settles on its own within a few minutes of application. Avoid rubbing the cream in vigorously — a gentle dabbing motion is sufficient. If irritation persists or worsens, discontinue use and consult your pharmacist or GP for further advice.
Who is eligible to use Zovirax cold sore cream?
Zovirax cold sore cream is suitable for adults and children aged 12 years and over who have cold sores on the lips or face caused by the herpes simplex virus. It is not recommended for children under 12, people with severely compromised immune systems without GP guidance, or for treating cold sores inside the mouth or on the genitals. If you are pregnant or breastfeeding, speak to your pharmacist before use.
What happens if I miss a dose of Zovirax cold sore cream?
If you forget to apply the cream at one of your scheduled times, apply it as soon as you remember and then continue with your regular schedule. Do not apply a double amount to make up for a missed application. Consistency is important — try to apply the cream at regular four-hourly intervals throughout the day for the best results.
What are the alternatives to Zovirax cold sore cream?
Alternatives to Zovirax cold sore cream include generic aciclovir 5% cream, which contains the same active ingredient at a lower price point, and penciclovir 1% cream (Vectavir), which is applied more frequently but over a shorter four-day course. For recurrent or severe outbreaks, your GP may consider prescribing oral aciclovir or valaciclovir tablets. You can explore related topical treatments in our creams and ointments collection.
How long does Zovirax cold sore cream take to work?
Zovirax cold sore cream is used for five days, and many people notice that the cold sore heals more quickly than it would without treatment, particularly when started early. Clinical studies have shown that aciclovir cream can reduce the duration of a cold sore episode when applied at the first sign of symptoms. If there is no improvement after ten days of use, consult your GP.
Can I use Zovirax cold sore cream during pregnancy?
If you are pregnant or breastfeeding, you should speak to your doctor or pharmacist before using Zovirax cold sore cream. Although topical aciclovir is only minimally absorbed through the skin and systemic exposure is very low, it is always sensible to seek professional advice before using any medicine during pregnancy. Your pharmacist can help you weigh up the benefits and any potential risks.
Can children use Zovirax cold sore cream?
Zovirax cold sore cream is not recommended for children under 12 years of age. For children aged 12 and over, it can be used in the same way as adults — five times daily for five days. If a younger child develops a cold sore, speak to your GP or pharmacist for appropriate advice and treatment options.
How long can you use Zovirax cold sore cream for?
The standard course of Zovirax cold sore cream is five days, which can be extended to ten days if the cold sore has not fully healed. It is not intended for long-term continuous use. If you are experiencing very frequent cold sore outbreaks — more than six per year — speak to your GP, who may consider oral antiviral therapy or other management strategies.
Does Zovirax cold sore cream interact with other medicines?
No clinically significant drug interactions are known at the topical doses of aciclovir used in Zovirax cold sore cream, as systemic absorption through the skin is very low. However, if you are already taking oral antiviral medicines such as aciclovir or valaciclovir tablets, let your pharmacist know before using this cream. Always inform your pharmacist of all medicines you are currently taking.
What are the latest studies on aciclovir cold sore cream?
Aciclovir 5% cream has been used clinically for decades and its efficacy in treating herpes simplex labialis is well established in published literature. Research consistently supports early application as the key factor in reducing outbreak duration and severity. For the most up-to-date clinical guidance, the NHS and BNF remain the primary reference sources for UK healthcare professionals and patients. You can also find related pain relief products if you need additional comfort during a cold sore outbreak.
