
The Story
What Are Perrigo Omeprazole 20mg Capsules?
If you've ever felt that familiar burning sensation rising up from your stomach after a meal, you'll know how uncomfortable heartburn can be. Omeprazole 20mg capsules are one of the most widely used over-the-counter treatments for heartburn and acid reflux in the UK. Perrigo's 14-pack offers a convenient, cost-effective way to manage these symptoms without needing a prescription. Each capsule contains 20mg of omeprazole, a proton pump inhibitor (PPI) that works directly on the stomach lining to reduce acid production at its source. You can also browse our full range of indigestion treatments if you're looking for additional options.
Heartburn affects a significant proportion of adults in the UK, with many experiencing symptoms regularly. Acid reflux occurs when stomach acid travels back up into the oesophagus, causing that characteristic burning discomfort. Omeprazole has been used clinically for decades and is well-established as an effective short-term treatment for these symptoms.
How Do Perrigo Heartburn Capsules Work in the Body?
Omeprazole belongs to a class of medicines called proton pump inhibitors. Rather than simply neutralising acid already present in the stomach — as antacids do — it targets the mechanism that produces acid in the first place. Here's how it works step by step:
- Omeprazole is absorbed from the gut into the bloodstream after you swallow the capsule.
- It travels to the parietal cells in the stomach lining, which are responsible for secreting hydrochloric acid.
- It irreversibly binds to and blocks the hydrogen-potassium ATPase enzyme — commonly called the "proton pump."
- With the pump blocked, significantly less acid is produced, reducing the acidity of stomach contents.
- This lower acid environment allows the oesophagus and stomach lining to recover from irritation.
Because omeprazole works at the source of acid production, its effects tend to last longer than antacids. It typically takes one to four days of regular use to reach its full effect, so it's best suited to ongoing symptom management rather than instant relief.
Who Is Perrigo Heartburn & Acid Reflux 20mg Suitable For?
These capsules are intended for adults aged 18 and over who experience frequent heartburn or acid reflux symptoms. They're particularly useful if you find that antacids provide only short-term relief and you need something that works over a longer period. That said, they're not appropriate for everyone.
This product may be suitable for you if:
- You are an adult aged 18 or over experiencing heartburn at least twice a week.
- You have been previously diagnosed with gastro-oesophageal reflux disease (GORD) and your doctor has recommended a PPI.
- You need short-term relief (up to 14 days) from acid reflux symptoms.
- You have not found adequate relief from antacid-based treatments alone.
It is not suitable for children under 18, people with difficulty swallowing, or those who have experienced unexplained weight loss, persistent vomiting, or blood in their stools — these symptoms require urgent medical assessment.
How Does Omeprazole Compare to Other Heartburn Treatments?
| Feature | Perrigo Omeprazole 20mg | Antacids (e.g. Gaviscon) |
|---|---|---|
| Mechanism | Blocks acid production (PPI) | Neutralises existing stomach acid |
| Onset of action | 1–4 days for full effect | Within minutes |
| Duration of effect | Up to 24 hours per dose | 1–3 hours |
| Best suited for | Frequent, ongoing heartburn | Occasional, mild heartburn |
How Should You Store Perrigo Heartburn Capsules?
Store these capsules below 25°C in a dry place, away from direct sunlight and moisture. Keep them in their original packaging and out of the reach and sight of children. Do not use after the expiry date printed on the pack. If you're managing multiple health conditions and storing several medicines, it's worth keeping everything organised — you might also find our vitamins and supplements range useful for supporting your overall wellbeing alongside treatment.
This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.
Perrigo Heartburn & Acid Reflux 20mg Capsules 14 Pack specifications
| Treatment category | Heartburn & Acid Reflux |
| Mechanism of action | Proton pump inhibitor (PPI) — reduces stomach acid production |
| Effective for | Heartburn, acid reflux, gastro-oesophageal reflux symptoms |
| Suitable for | Adults aged 18 and over |
| Active ingredient | Omeprazole 20mg |
| Pack size | 14 capsules |
| Strength | 20mg |
| UK classification | Pharmacy (P) medicine |
| Drug class | Proton pump inhibitor |
| Preparation | Gastro-resistant capsule |
| Route of administration | Oral |
Specifications of Perrigo Heartburn & Acid Reflux 20mg Capsules 14 Pack
What Is Perrigo Heartburn & Acid Reflux 20mg and What Is It Used For?
Perrigo Heartburn & Acid Reflux 20mg Capsules contain omeprazole, a proton pump inhibitor licensed for the short-term OTC treatment of reflux symptoms in adults. It is used to relieve the burning sensation in the chest or throat caused by stomach acid travelling back up into the oesophagus — a condition commonly known as acid reflux or heartburn. It may also help with the sour taste in the mouth and discomfort after eating that many people with reflux experience. This product is for adults aged 18 and over and should be used for no longer than 14 days at a time without medical supervision.
What Do You Need to Know Before Using Perrigo Heartburn Capsules?
Before taking these capsules, it's important to check whether they are appropriate for you. Do not take this medicine if any of the following apply:
- You are allergic to omeprazole, any other PPI (such as lansoprazole or pantoprazole), or any of the capsule's other ingredients.
- You are under 18 years of age.
- You are taking medicines containing nelfinavir (used to treat HIV infection).
- You have experienced unexplained weight loss, difficulty swallowing, persistent vomiting, or blood in your vomit or stools — seek urgent medical advice.
- You have severe liver problems (unless under medical supervision).
The following medicines may interact with omeprazole. Tell your pharmacist or doctor if you are taking:
- Clopidogrel (a blood-thinning medicine) — omeprazole may reduce its effectiveness.
- Methotrexate — omeprazole may increase methotrexate levels in the blood.
- Warfarin or other anticoagulants — monitoring may be required.
- Ketoconazole, itraconazole, or other antifungals — absorption may be affected.
- Digoxin — omeprazole may increase digoxin levels slightly.
- Cilostazol, diazepam, or phenytoin — plasma levels may be altered.
How Should You Use Perrigo Heartburn & Acid Reflux 20mg Capsules?
Always use this medicine exactly as described in the patient information leaflet. If you are unsure, check with your pharmacist. Follow these steps:
- Take one capsule by mouth once daily.
- Swallow the capsule whole with a glass of water — do not crush, chew, or open it.
- Take it 30 to 60 minutes before a meal, ideally in the morning.
- Continue for up to 14 days or until symptoms resolve, whichever comes first.
- If symptoms have not improved after 14 days, stop taking the capsules and consult your doctor.
| Indication | Age Group | Dose | Frequency |
|---|---|---|---|
| Heartburn / acid reflux | Adults 18+ | 20mg (1 capsule) | Once daily, up to 14 days |
| Children under 18 | Under 18 | Not applicable | Not recommended |
If you're also managing other digestive concerns, you may find it helpful to explore our IBS and cramps range for complementary support.
What Are the Possible Side Effects of Perrigo Heartburn Capsules?
Like all medicines, omeprazole can cause side effects, although not everyone experiences them. Most are mild and resolve on their own.
Common side effects (may affect up to 1 in 10 people):
- Headache
- Diarrhoea
- Stomach pain or discomfort
- Constipation
- Nausea or vomiting
- Flatulence
Less common side effects (may affect up to 1 in 100 people):
- Dizziness
- Dry mouth
- Skin rash or itching
- Peripheral oedema (swelling of the ankles or feet)
- Disturbed sleep
Stop taking the capsules and seek immediate medical attention if you develop signs of a serious allergic reaction, such as swelling of the face, lips, tongue or throat, difficulty breathing, or a severe skin reaction. Long-term use of PPIs has been associated with low magnesium levels and an increased risk of bone fractures — this is more relevant to prescription-strength, long-term use rather than a 14-day OTC course.
How Should You Store Perrigo Heartburn & Acid Reflux 20mg Capsules?
Correct storage helps maintain the quality and safety of your medicine. Follow these guidelines:
- Store below 25°C in a dry place.
- Keep away from direct sunlight and moisture.
- Store in the original blister packaging until use.
- Keep out of the reach and sight of children.
- Do not use after the expiry date printed on the pack.
- Do not dispose of medicines via wastewater or household waste — return unused capsules to your pharmacy.
If you're looking for further digestive health support or want to manage related symptoms, our sickness and nausea range may also be of interest.
References
- https://www.nhs.uk/medicines/omeprazole/
- https://www.nhs.uk/conditions/heartburn-and-acid-reflux/
- https://www.nhs.uk/conditions/gastro-oesophageal-reflux-disease-gord/
- https://www.nhs.uk/medicines/omeprazole/side-effects-of-omeprazole/
- https://www.nhs.uk/medicines/omeprazole/who-can-and-cannot-take-omeprazole/
- https://bnf.nice.org.uk/drugs/omeprazole/
Written and reviewed by our qualified team
Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.
Frequently Asked Questions
Where can I buy Perrigo omeprazole 20mg capsules online in the UK?
You can buy Perrigo Heartburn & Acid Reflux 20mg Capsules directly from Cured Pharmacy, a GPhC-registered UK online pharmacy. No prescription is needed — they are available as an over-the-counter pharmacy medicine for adults aged 18 and over. Simply add to your basket and complete a short health check at checkout to ensure suitability.
How do omeprazole 20mg capsules work for heartburn?
Omeprazole works by irreversibly blocking the proton pumps in the stomach lining — the enzymes responsible for producing hydrochloric acid. By reducing the amount of acid your stomach makes, it relieves the burning sensation of heartburn and allows the oesophagus to recover. Unlike antacids, which neutralise acid already present, omeprazole tackles the root cause of excess acid production.
How do I take Perrigo Heartburn & Acid Reflux 20mg Capsules step by step?
Take one capsule once daily, swallowed whole with a full glass of water — do not crush or chew it. It's best taken 30 to 60 minutes before your first meal of the day for optimal absorption. Continue for up to 14 days; if symptoms persist beyond this, stop and consult your GP or pharmacist.
What is the best time to take omeprazole 20mg capsules?
The most effective time to take omeprazole is in the morning, 30 to 60 minutes before breakfast. Taking it before eating allows the medicine to be absorbed and reach the proton pumps while they are most active — which is when you start eating. Consistency matters, so try to take it at the same time each day throughout your 14-day course.
What are the side effects of Perrigo Heartburn & Acid Reflux 20mg Capsules?
Common side effects include headache, diarrhoea, stomach pain, constipation, nausea, and flatulence. Less commonly, you may experience dizziness, dry mouth, or a skin rash. If you develop signs of a serious allergic reaction — such as facial swelling, difficulty breathing, or a severe rash — stop taking the capsules immediately and seek urgent medical attention.
How do I manage side effects of omeprazole 20mg capsules?
Most side effects are mild and tend to resolve without any specific treatment. For headaches, a standard over-the-counter painkiller may help — you can browse our pain relief range for suitable options. If diarrhoea or stomach discomfort is troublesome, staying well hydrated and eating bland foods can help; if symptoms are severe or persistent, speak to your pharmacist.
Who should not take Perrigo Heartburn & Acid Reflux 20mg Capsules?
This product is not suitable for anyone under 18, people with a known allergy to omeprazole or other proton pump inhibitors, or those taking nelfinavir (an HIV medicine). You should also avoid it if you have unexplained weight loss, difficulty swallowing, persistent vomiting, or blood in your stools — these symptoms need urgent medical investigation rather than self-treatment. Always read the full patient information leaflet before use.
Can I take omeprazole 20mg capsules during pregnancy or breastfeeding?
You should not take omeprazole during pregnancy or while breastfeeding without first consulting your doctor or midwife. Although omeprazole is sometimes used under medical supervision during pregnancy, self-medicating with an OTC product is not recommended. Your GP can advise on the safest option for managing heartburn during pregnancy.
What happens if I miss a dose of Perrigo Heartburn Capsules?
If you forget to take your capsule, take it as soon as you remember — provided it is still before your next meal. If it is close to the time of your next scheduled dose, skip the missed one and carry on as normal. Never take two capsules at once to make up for a missed dose.
How long can you take omeprazole 20mg capsules for?
As an OTC medicine, Perrigo Heartburn & Acid Reflux 20mg Capsules should not be taken for more than 14 consecutive days without medical advice. If your symptoms return after completing a course, or if you find you need repeated courses, you should speak to your GP. Long-term use of PPIs is only appropriate under medical supervision.
What are alternatives to omeprazole 20mg capsules for acid reflux?
Alternatives include other OTC proton pump inhibitors such as lansoprazole 15mg, or H2 receptor antagonists such as famotidine, which work differently but also reduce acid. Antacids like Gaviscon or Rennie provide faster but shorter-lasting relief and are better suited to occasional symptoms. Your pharmacist can help you choose the most appropriate option based on your symptoms and medical history.
Does omeprazole interact with any other medicines?
Yes — omeprazole can interact with several medicines, including clopidogrel (where it may reduce effectiveness), methotrexate, warfarin, ketoconazole, digoxin, and phenytoin. Always tell your pharmacist about all medicines, supplements, and herbal remedies you are taking before starting omeprazole. If you take clopidogrel, your doctor may recommend an alternative acid-reducing medicine.
Is Perrigo omeprazole the same as prescription omeprazole?
Yes — the active ingredient, omeprazole 20mg, is the same whether dispensed on prescription or purchased OTC. The key difference is that prescription omeprazole may be available in higher doses (such as 40mg) and for longer treatment durations under medical supervision. The OTC 20mg pack is licensed specifically for short-term self-treatment of heartburn and reflux symptoms in adults.
What are the latest findings on omeprazole and long-term use?
Research has highlighted that long-term PPI use (beyond recommended OTC durations) may be associated with a small increased risk of low magnesium levels, vitamin B12 deficiency, and bone fractures. These concerns are primarily relevant to long-term prescription use rather than a standard 14-day OTC course. If you feel you need ongoing acid suppression, speak to your GP for a full assessment.
Can lifestyle changes help alongside omeprazole 20mg capsules?
Absolutely — lifestyle adjustments can make a meaningful difference to heartburn and acid reflux symptoms. The NHS recommends eating smaller meals, avoiding fatty or spicy foods, not lying down within three hours of eating, raising the head of your bed, and maintaining a healthy weight. Reducing alcohol and stopping smoking can also significantly reduce symptoms. These changes work well alongside a short course of omeprazole for more complete relief.
Description
What Are Perrigo Omeprazole 20mg Capsules?
If you've ever felt that familiar burning sensation rising up from your stomach after a meal, you'll know how uncomfortable heartburn can be. Omeprazole 20mg capsules are one of the most widely used over-the-counter treatments for heartburn and acid reflux in the UK. Perrigo's 14-pack offers a convenient, cost-effective way to manage these symptoms without needing a prescription. Each capsule contains 20mg of omeprazole, a proton pump inhibitor (PPI) that works directly on the stomach lining to reduce acid production at its source. You can also browse our full range of indigestion treatments if you're looking for additional options.
Heartburn affects a significant proportion of adults in the UK, with many experiencing symptoms regularly. Acid reflux occurs when stomach acid travels back up into the oesophagus, causing that characteristic burning discomfort. Omeprazole has been used clinically for decades and is well-established as an effective short-term treatment for these symptoms.
How Do Perrigo Heartburn Capsules Work in the Body?
Omeprazole belongs to a class of medicines called proton pump inhibitors. Rather than simply neutralising acid already present in the stomach — as antacids do — it targets the mechanism that produces acid in the first place. Here's how it works step by step:
- Omeprazole is absorbed from the gut into the bloodstream after you swallow the capsule.
- It travels to the parietal cells in the stomach lining, which are responsible for secreting hydrochloric acid.
- It irreversibly binds to and blocks the hydrogen-potassium ATPase enzyme — commonly called the "proton pump."
- With the pump blocked, significantly less acid is produced, reducing the acidity of stomach contents.
- This lower acid environment allows the oesophagus and stomach lining to recover from irritation.
Because omeprazole works at the source of acid production, its effects tend to last longer than antacids. It typically takes one to four days of regular use to reach its full effect, so it's best suited to ongoing symptom management rather than instant relief.
Who Is Perrigo Heartburn & Acid Reflux 20mg Suitable For?
These capsules are intended for adults aged 18 and over who experience frequent heartburn or acid reflux symptoms. They're particularly useful if you find that antacids provide only short-term relief and you need something that works over a longer period. That said, they're not appropriate for everyone.
This product may be suitable for you if:
- You are an adult aged 18 or over experiencing heartburn at least twice a week.
- You have been previously diagnosed with gastro-oesophageal reflux disease (GORD) and your doctor has recommended a PPI.
- You need short-term relief (up to 14 days) from acid reflux symptoms.
- You have not found adequate relief from antacid-based treatments alone.
It is not suitable for children under 18, people with difficulty swallowing, or those who have experienced unexplained weight loss, persistent vomiting, or blood in their stools — these symptoms require urgent medical assessment.
How Does Omeprazole Compare to Other Heartburn Treatments?
| Feature | Perrigo Omeprazole 20mg | Antacids (e.g. Gaviscon) |
|---|---|---|
| Mechanism | Blocks acid production (PPI) | Neutralises existing stomach acid |
| Onset of action | 1–4 days for full effect | Within minutes |
| Duration of effect | Up to 24 hours per dose | 1–3 hours |
| Best suited for | Frequent, ongoing heartburn | Occasional, mild heartburn |
How Should You Store Perrigo Heartburn Capsules?
Store these capsules below 25°C in a dry place, away from direct sunlight and moisture. Keep them in their original packaging and out of the reach and sight of children. Do not use after the expiry date printed on the pack. If you're managing multiple health conditions and storing several medicines, it's worth keeping everything organised — you might also find our vitamins and supplements range useful for supporting your overall wellbeing alongside treatment.
This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.
Perrigo Heartburn & Acid Reflux 20mg Capsules 14 Pack specifications
| Treatment category | Heartburn & Acid Reflux |
| Mechanism of action | Proton pump inhibitor (PPI) — reduces stomach acid production |
| Effective for | Heartburn, acid reflux, gastro-oesophageal reflux symptoms |
| Suitable for | Adults aged 18 and over |
| Active ingredient | Omeprazole 20mg |
| Pack size | 14 capsules |
| Strength | 20mg |
| UK classification | Pharmacy (P) medicine |
| Drug class | Proton pump inhibitor |
| Preparation | Gastro-resistant capsule |
| Route of administration | Oral |
Specifications of Perrigo Heartburn & Acid Reflux 20mg Capsules 14 Pack
What Is Perrigo Heartburn & Acid Reflux 20mg and What Is It Used For?
Perrigo Heartburn & Acid Reflux 20mg Capsules contain omeprazole, a proton pump inhibitor licensed for the short-term OTC treatment of reflux symptoms in adults. It is used to relieve the burning sensation in the chest or throat caused by stomach acid travelling back up into the oesophagus — a condition commonly known as acid reflux or heartburn. It may also help with the sour taste in the mouth and discomfort after eating that many people with reflux experience. This product is for adults aged 18 and over and should be used for no longer than 14 days at a time without medical supervision.
What Do You Need to Know Before Using Perrigo Heartburn Capsules?
Before taking these capsules, it's important to check whether they are appropriate for you. Do not take this medicine if any of the following apply:
- You are allergic to omeprazole, any other PPI (such as lansoprazole or pantoprazole), or any of the capsule's other ingredients.
- You are under 18 years of age.
- You are taking medicines containing nelfinavir (used to treat HIV infection).
- You have experienced unexplained weight loss, difficulty swallowing, persistent vomiting, or blood in your vomit or stools — seek urgent medical advice.
- You have severe liver problems (unless under medical supervision).
The following medicines may interact with omeprazole. Tell your pharmacist or doctor if you are taking:
- Clopidogrel (a blood-thinning medicine) — omeprazole may reduce its effectiveness.
- Methotrexate — omeprazole may increase methotrexate levels in the blood.
- Warfarin or other anticoagulants — monitoring may be required.
- Ketoconazole, itraconazole, or other antifungals — absorption may be affected.
- Digoxin — omeprazole may increase digoxin levels slightly.
- Cilostazol, diazepam, or phenytoin — plasma levels may be altered.
How Should You Use Perrigo Heartburn & Acid Reflux 20mg Capsules?
Always use this medicine exactly as described in the patient information leaflet. If you are unsure, check with your pharmacist. Follow these steps:
- Take one capsule by mouth once daily.
- Swallow the capsule whole with a glass of water — do not crush, chew, or open it.
- Take it 30 to 60 minutes before a meal, ideally in the morning.
- Continue for up to 14 days or until symptoms resolve, whichever comes first.
- If symptoms have not improved after 14 days, stop taking the capsules and consult your doctor.
| Indication | Age Group | Dose | Frequency |
|---|---|---|---|
| Heartburn / acid reflux | Adults 18+ | 20mg (1 capsule) | Once daily, up to 14 days |
| Children under 18 | Under 18 | Not applicable | Not recommended |
If you're also managing other digestive concerns, you may find it helpful to explore our IBS and cramps range for complementary support.
What Are the Possible Side Effects of Perrigo Heartburn Capsules?
Like all medicines, omeprazole can cause side effects, although not everyone experiences them. Most are mild and resolve on their own.
Common side effects (may affect up to 1 in 10 people):
- Headache
- Diarrhoea
- Stomach pain or discomfort
- Constipation
- Nausea or vomiting
- Flatulence
Less common side effects (may affect up to 1 in 100 people):
- Dizziness
- Dry mouth
- Skin rash or itching
- Peripheral oedema (swelling of the ankles or feet)
- Disturbed sleep
Stop taking the capsules and seek immediate medical attention if you develop signs of a serious allergic reaction, such as swelling of the face, lips, tongue or throat, difficulty breathing, or a severe skin reaction. Long-term use of PPIs has been associated with low magnesium levels and an increased risk of bone fractures — this is more relevant to prescription-strength, long-term use rather than a 14-day OTC course.
How Should You Store Perrigo Heartburn & Acid Reflux 20mg Capsules?
Correct storage helps maintain the quality and safety of your medicine. Follow these guidelines:
- Store below 25°C in a dry place.
- Keep away from direct sunlight and moisture.
- Store in the original blister packaging until use.
- Keep out of the reach and sight of children.
- Do not use after the expiry date printed on the pack.
- Do not dispose of medicines via wastewater or household waste — return unused capsules to your pharmacy.
If you're looking for further digestive health support or want to manage related symptoms, our sickness and nausea range may also be of interest.
References
- https://www.nhs.uk/medicines/omeprazole/
- https://www.nhs.uk/conditions/heartburn-and-acid-reflux/
- https://www.nhs.uk/conditions/gastro-oesophageal-reflux-disease-gord/
- https://www.nhs.uk/medicines/omeprazole/side-effects-of-omeprazole/
- https://www.nhs.uk/medicines/omeprazole/who-can-and-cannot-take-omeprazole/
- https://bnf.nice.org.uk/drugs/omeprazole/
Written and reviewed by our qualified team
Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.
Frequently Asked Questions
Where can I buy Perrigo omeprazole 20mg capsules online in the UK?
You can buy Perrigo Heartburn & Acid Reflux 20mg Capsules directly from Cured Pharmacy, a GPhC-registered UK online pharmacy. No prescription is needed — they are available as an over-the-counter pharmacy medicine for adults aged 18 and over. Simply add to your basket and complete a short health check at checkout to ensure suitability.
How do omeprazole 20mg capsules work for heartburn?
Omeprazole works by irreversibly blocking the proton pumps in the stomach lining — the enzymes responsible for producing hydrochloric acid. By reducing the amount of acid your stomach makes, it relieves the burning sensation of heartburn and allows the oesophagus to recover. Unlike antacids, which neutralise acid already present, omeprazole tackles the root cause of excess acid production.
How do I take Perrigo Heartburn & Acid Reflux 20mg Capsules step by step?
Take one capsule once daily, swallowed whole with a full glass of water — do not crush or chew it. It's best taken 30 to 60 minutes before your first meal of the day for optimal absorption. Continue for up to 14 days; if symptoms persist beyond this, stop and consult your GP or pharmacist.
What is the best time to take omeprazole 20mg capsules?
The most effective time to take omeprazole is in the morning, 30 to 60 minutes before breakfast. Taking it before eating allows the medicine to be absorbed and reach the proton pumps while they are most active — which is when you start eating. Consistency matters, so try to take it at the same time each day throughout your 14-day course.
What are the side effects of Perrigo Heartburn & Acid Reflux 20mg Capsules?
Common side effects include headache, diarrhoea, stomach pain, constipation, nausea, and flatulence. Less commonly, you may experience dizziness, dry mouth, or a skin rash. If you develop signs of a serious allergic reaction — such as facial swelling, difficulty breathing, or a severe rash — stop taking the capsules immediately and seek urgent medical attention.
How do I manage side effects of omeprazole 20mg capsules?
Most side effects are mild and tend to resolve without any specific treatment. For headaches, a standard over-the-counter painkiller may help — you can browse our pain relief range for suitable options. If diarrhoea or stomach discomfort is troublesome, staying well hydrated and eating bland foods can help; if symptoms are severe or persistent, speak to your pharmacist.
Who should not take Perrigo Heartburn & Acid Reflux 20mg Capsules?
This product is not suitable for anyone under 18, people with a known allergy to omeprazole or other proton pump inhibitors, or those taking nelfinavir (an HIV medicine). You should also avoid it if you have unexplained weight loss, difficulty swallowing, persistent vomiting, or blood in your stools — these symptoms need urgent medical investigation rather than self-treatment. Always read the full patient information leaflet before use.
Can I take omeprazole 20mg capsules during pregnancy or breastfeeding?
You should not take omeprazole during pregnancy or while breastfeeding without first consulting your doctor or midwife. Although omeprazole is sometimes used under medical supervision during pregnancy, self-medicating with an OTC product is not recommended. Your GP can advise on the safest option for managing heartburn during pregnancy.
What happens if I miss a dose of Perrigo Heartburn Capsules?
If you forget to take your capsule, take it as soon as you remember — provided it is still before your next meal. If it is close to the time of your next scheduled dose, skip the missed one and carry on as normal. Never take two capsules at once to make up for a missed dose.
How long can you take omeprazole 20mg capsules for?
As an OTC medicine, Perrigo Heartburn & Acid Reflux 20mg Capsules should not be taken for more than 14 consecutive days without medical advice. If your symptoms return after completing a course, or if you find you need repeated courses, you should speak to your GP. Long-term use of PPIs is only appropriate under medical supervision.
What are alternatives to omeprazole 20mg capsules for acid reflux?
Alternatives include other OTC proton pump inhibitors such as lansoprazole 15mg, or H2 receptor antagonists such as famotidine, which work differently but also reduce acid. Antacids like Gaviscon or Rennie provide faster but shorter-lasting relief and are better suited to occasional symptoms. Your pharmacist can help you choose the most appropriate option based on your symptoms and medical history.
Does omeprazole interact with any other medicines?
Yes — omeprazole can interact with several medicines, including clopidogrel (where it may reduce effectiveness), methotrexate, warfarin, ketoconazole, digoxin, and phenytoin. Always tell your pharmacist about all medicines, supplements, and herbal remedies you are taking before starting omeprazole. If you take clopidogrel, your doctor may recommend an alternative acid-reducing medicine.
Is Perrigo omeprazole the same as prescription omeprazole?
Yes — the active ingredient, omeprazole 20mg, is the same whether dispensed on prescription or purchased OTC. The key difference is that prescription omeprazole may be available in higher doses (such as 40mg) and for longer treatment durations under medical supervision. The OTC 20mg pack is licensed specifically for short-term self-treatment of heartburn and reflux symptoms in adults.
What are the latest findings on omeprazole and long-term use?
Research has highlighted that long-term PPI use (beyond recommended OTC durations) may be associated with a small increased risk of low magnesium levels, vitamin B12 deficiency, and bone fractures. These concerns are primarily relevant to long-term prescription use rather than a standard 14-day OTC course. If you feel you need ongoing acid suppression, speak to your GP for a full assessment.
Can lifestyle changes help alongside omeprazole 20mg capsules?
Absolutely — lifestyle adjustments can make a meaningful difference to heartburn and acid reflux symptoms. The NHS recommends eating smaller meals, avoiding fatty or spicy foods, not lying down within three hours of eating, raising the head of your bed, and maintaining a healthy weight. Reducing alcohol and stopping smoking can also significantly reduce symptoms. These changes work well alongside a short course of omeprazole for more complete relief.













