Night Nurse Liquid 160ml

What Is Night Nurse Liquid and How Does It Help?

When a cold or flu hits at night, it can feel relentless. The coughing, the blocked nose, the aching — all of it conspiring to keep you awake when your body needs rest most. Night nurse liquid is a well-established over-the-counter medicine designed specifically to tackle those night-time cold and flu symptoms so you can actually get some sleep. Available from Cured Pharmacy's cold and flu range, this 160ml liquid formulation contains three active ingredients that work together to relieve multiple symptoms at once.

Each 20ml dose contains paracetamol 1000mg, promethazine hydrochloride 20mg, and dextromethorphan hydrobromide 15mg. These are not random additions — each one targets a specific symptom of cold and flu, making this a multi-action remedy rather than a single-symptom fix. It is suitable for adults and young people aged 16 and over.

How Does Night Nurse Liquid Work in the Body?

Understanding how a medicine works helps you use it more confidently. Night Nurse Liquid works through three distinct mechanisms:

• Paracetamol — reduces fever (pyrexia) and relieves pain such as headaches, sore throat, and body aches associated with cold and flu.
• Promethazine hydrochloride — a first-generation antihistamine that reduces nasal congestion and has a sedative effect, helping you fall asleep more easily when symptoms would otherwise keep you awake.
• Dextromethorphan hydrobromide — an antitussive (cough suppressant) that acts on the cough centre in the brain to reduce the urge to cough, particularly the dry, irritating cough common with viral upper respiratory tract infections.

Together, these three ingredients address the most disruptive night-time cold and flu symptoms simultaneously. That is why many people find it more effective at night than single-ingredient remedies.

Who Is Night Nurse Liquid Suitable For?

This medicine is intended for adults and young people aged 16 years and over who are experiencing cold or flu symptoms that are disrupting their sleep. It is particularly useful if you have a combination of symptoms rather than just one. That said, it is not appropriate for everyone.

Night Nurse Liquid may be suitable if you:

• Are aged 16 or over and experiencing cold or flu symptoms at night
• Have a dry, persistent cough that is keeping you awake
• Are suffering from a blocked or runny nose alongside other symptoms
• Have a mild fever, sore throat, or body aches associated with a cold or flu

It is not suitable for children under 16, people with certain liver or kidney conditions, or those taking monoamine oxidase inhibitors (MAOIs). Always read the label carefully before use.

How Does Night Nurse Liquid Compare to Day Nurse?

How Should You Store Night Nurse Liquid?

Store night nurse liquid below 25°C in a cool, dry place away from direct sunlight. Keep the bottle tightly closed and out of the reach and sight of children at all times. Do not use the product after the expiry date printed on the label or bottle. If you are unsure whether a medicine is still safe to use, your pharmacist can advise you — and you can also browse our sleep aid collection for related products.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

What Is Night Nurse Liquid and What Is It Used For?

Night Nurse Liquid 160ml is an over-the-counter combination medicine used to relieve the symptoms of colds and flu at night. It contains three active ingredients — paracetamol, promethazine hydrochloride, and dextromethorphan hydrobromide — each targeting a different symptom. It is used to relieve fever, pain (such as headache and sore throat), dry cough, and nasal congestion, while also helping you sleep through the discomfort. It is classified as a Pharmacy (P) medicine in the UK, meaning it can be purchased without a prescription but should be used under pharmacist guidance.

What Do You Need to Know Before Using Night Nurse Liquid?

Before taking this medicine, it is important to check whether it is appropriate for you. There are several situations where Night Nurse Liquid should not be used or should only be used with caution.

Do not take Night Nurse Liquid if you:

• Are under 16 years of age
• Are allergic to paracetamol, promethazine, dextromethorphan, or any other ingredient in the product
• Are taking or have taken monoamine oxidase inhibitors (MAOIs) within the last 14 days
• Have severe liver or kidney disease
• Are pregnant or breastfeeding without first consulting your GP
• Have a condition causing excessive mucus production (productive cough) — dextromethorphan is not appropriate for wet coughs

Known drug interactions — take care if you are also taking:

• Other medicines containing paracetamol (risk of overdose)
• Sedatives, sleeping tablets, or anxiolytics (increased drowsiness)
• Antidepressants, particularly SSRIs or MAOIs (risk of serotonin syndrome with dextromethorphan)
• Anticoagulants such as warfarin (paracetamol may affect INR at higher doses)
• Anticholinergic medicines (additive effects with promethazine)

If you are unsure about interactions, speak to your pharmacist before purchasing. You can also explore our pain relief collection for paracetamol-only alternatives if a combination product is not suitable for you.

How Should You Use Night Nurse Liquid?

Always use Night Nurse Liquid exactly as directed on the label or as advised by your pharmacist. This medicine is for night-time use only — do not take it during the day if you need to drive or operate machinery.

1. Shake the bottle gently before use.
2. Measure 20ml using the measuring cup provided.
3. Take the dose at bedtime only.
4. Do not take more than one dose in any 24-hour period.
5. Do not take with alcohol or other sedating medicines.
6. Do not take alongside any other paracetamol-containing product.

What Are the Possible Side Effects of Night Nurse Liquid?

Like all medicines, Night Nurse Liquid can cause side effects, although not everyone experiences them. The promethazine component is responsible for most of the side effects listed below.

Common side effects:

• Drowsiness or sedation (this is expected and intentional at night)
• Dry mouth
• Dizziness
• Blurred vision
• Difficulty urinating

Less common side effects:

• Nausea or stomach upset
• Headache (on waking)
• Skin sensitivity to sunlight (photosensitivity) — relevant if you take it and are exposed to sunlight the following day
• Confusion, particularly in older adults
• Palpitations (rare)

If you experience a serious allergic reaction — such as swelling of the face, lips, or throat, difficulty breathing, or a severe skin rash — stop taking the medicine and seek emergency medical attention immediately. You can find further NHS guidance on cold and flu symptoms and when to seek help via the NHS website.

How Should You Store Night Nurse Liquid?

Correct storage helps maintain the safety and effectiveness of the medicine. Follow these instructions carefully:

• Store below 25°C in a cool, dry place
• Keep away from direct sunlight and heat sources
• Keep the bottle tightly closed when not in use
• Store out of the reach and sight of children
• Do not use after the expiry date printed on the bottle or carton
• Do not dispose of medicines via wastewater or household waste — return unused medicine to your pharmacy

If you are managing multiple health conditions and need to keep track of several medicines, our vitamins and supplements collection may also be of interest for supporting your general wellbeing during recovery.