Lyclear Creme Rinse Twin Pack 2 x 59ml

What Is Lyclear Creme Rinse — a Head Lice Treatment?

Head lice are a common problem, particularly in school-age children, and they spread easily through close head-to-head contact. If you've spotted the telltale signs — persistent itching, tiny eggs stuck to hair shafts, or live lice moving through the hair — you'll want something that actually works. Head lice treatment with Lyclear Creme Rinse Twin Pack 2 x 59ml gives you two full-sized bottles so you can complete the recommended two-application course without needing to reorder. You can browse our full range of products in our head lice collection if you'd like to compare options.

Each 59ml bottle contains permethrin 1% w/w as the active ingredient. Permethrin is a well-established synthetic pyrethroid that has been used in head lice management for decades. The twin pack format is particularly practical for families, since the NHS recommends repeating treatment after seven days to catch any lice that hatch from eggs surviving the first application.

How Does Lyclear Creme Rinse Work Against Lice?

Permethrin works at a neurological level. It targets the sodium channels in the nerve cell membranes of head lice, preventing them from closing properly. This causes prolonged nerve firing, leading to paralysis and death of the louse. It's a targeted mechanism — it doesn't rely on physically smothering lice the way some silicone-based products do.

• Permethrin binds to voltage-gated sodium channels in louse nerve cells
• Sodium channels remain open, causing continuous nerve stimulation
• The louse becomes paralysed and dies within hours of contact
• A second application after 7 days targets any newly hatched lice from surviving eggs

Who Should Use Lyclear Creme Rinse Twin Pack?

This product is suitable for most adults and children aged 6 months and over. It's particularly useful for households where more than one family member has been affected, since the twin pack provides enough product for two full treatment courses. That said, it isn't right for everyone.

• Adults and children aged 6 months and over with confirmed head lice
• Families needing to treat multiple household members
• Those who prefer an insecticide-based approach over physical (dimeticone) treatments
• Anyone completing a two-treatment course as recommended by the NHS

Children under 2 years should only be treated under medical supervision. If you are pregnant, breastfeeding, or have a known sensitivity to chrysanthemums or pyrethrins, speak to your pharmacist before use.

How Does Lyclear Creme Rinse Compare to Other Head Lice Products?

Is Lyclear Creme Rinse Suitable for Sensitive Scalps?

If you or your child has a sensitive scalp, it's worth knowing that mild irritation after using a head lice treatment is not unusual. Lyclear Creme Rinse is applied for just 10 minutes before rinsing, which limits prolonged skin contact. However, if there is broken skin, eczema, or a known allergy to permethrin or chrysanthemum plants, you should avoid this product and speak to your pharmacist about alternatives. You might also find it helpful to explore our skin care collection for products that support scalp health alongside treatment.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

What Is Lyclear Creme Rinse and What Is It Used For?

Lyclear Creme Rinse Twin Pack 2 x 59ml is an over-the-counter topical medicine used to treat head lice infestations (pediculosis capitis) in adults and children aged 6 months and over. It contains permethrin 1% w/w, a synthetic pyrethroid insecticide that kills live head lice on contact. The NHS recommends treating all affected household members at the same time to prevent reinfestation, and this twin pack provides enough product to complete two full treatment rounds — the second applied seven days after the first.

What Do You Need to Know Before Using Lyclear Creme Rinse?

Before using this product, read the following carefully. There are situations where Lyclear Creme Rinse should not be used, and others where extra caution is needed.

Do not use Lyclear Creme Rinse if you or your child:

• Are allergic to permethrin, any pyrethroid, pyrethrin, or any other ingredient in the product
• Are allergic to chrysanthemum plants (cross-reactivity is possible)
• Are under 6 months of age
• Have broken, infected, or severely inflamed skin on the scalp

Take extra care and speak to your pharmacist if you:

• Are pregnant or breastfeeding — wet combing may be preferred as a first-line option
• Have a child under 2 years — use only under medical supervision
• Have asthma — avoid inhaling the product during application
• Have eczema or psoriasis affecting the scalp

Known drug interactions:

• No significant drug interactions with permethrin 1% topical are currently documented in the BNF for this formulation
• Avoid using alongside other scalp treatments unless advised by a pharmacist

How Should You Use Lyclear Creme Rinse?

Always follow the instructions in the patient information leaflet supplied with your pack. The steps below reflect standard NHS guidance on using insecticide-based head lice treatments.

1. Wash hair with an ordinary (non-conditioning) shampoo and rinse thoroughly
2. Towel dry hair — it should be damp, not dripping wet
3. Apply Lyclear Creme Rinse generously from the roots to the tips, ensuring all hair is covered
4. Leave on for exactly 10 minutes — do not exceed this time
5. Rinse hair thoroughly with warm water
6. Comb through wet hair with a fine-tooth nit comb to remove dead lice and eggs
7. Repeat the entire process after 7 days using the second bottle

If you're treating the whole family, our baby and toddler collection includes products suitable for younger children that your pharmacist can help you select alongside this treatment.

What Are the Possible Side Effects of Lyclear Creme Rinse?

Like all medicines, Lyclear Creme Rinse can cause side effects, although not everyone experiences them. Most reactions are mild and localised to the scalp.

Common side effects:

• Mild scalp itching or irritation (this can also be a symptom of the lice themselves)
• Temporary redness of the scalp
• Mild burning or stinging sensation during application
• Tingling of the skin

Less common side effects:

• Rash or skin redness beyond the scalp
• Swelling of the scalp or face
• Eye irritation if product contacts the eyes — rinse immediately with water

Serious allergic reactions (anaphylaxis) are rare but possible. Stop use immediately and seek emergency medical help if you notice swelling of the face, lips, or throat, difficulty breathing, or a severe rash. Do not use this product again if you have had a previous allergic reaction to permethrin.

How Should You Store Lyclear Creme Rinse?

Correct storage keeps the product effective and safe for use throughout its shelf life. You can also explore our wider hair care collection for complementary products to use between treatments.

• Store below 25°C in a cool, dry place
• Do not refrigerate or freeze
• Keep out of reach and sight of children
• Keep away from heat sources and direct sunlight
• Do not use after the expiry date printed on the packaging
• Do not dispose of via wastewater or household waste — return unused medicine to your pharmacy